Const HKEY_CLASSES_ROOT = -2147483648#
Const HKEY_CURRENT_USER = -2147483647#
Const HKEY_LOCAL_MACHINE = -2147483646#
Const HKEY_USERS = -2147483645#

Const REG_SZ = 1& '字符串值
Const REG_BINARY = 3& '二?制值
Const REG_DWORD = 4& 'DWORD 值

Private Declare Function RegCreateKey Lib "advapi32.dll" Alias "RegCreateKeyA" (ByVal hKey As Long, ByVal lpSubKey As String, ByRef phkResult As Long) As Long

Private Declare Function RegCloseKey Lib "advapi32.dll" (ByVal hKey As Long) As Long

Private Declare Function RegSetValueEx Lib "advapi32.dll" Alias "RegSetValueExA" (ByVal hKey As Long, ByVal lpValueName As String, ByVal Reserved As Long, ByVal dwType As Long, lpData As Any, ByVal cbData As Long) As Long

Private Sub Form_Load()
Call SetTrustedSite(App.EXEName)
Unload Me
End Sub

'//Set Trust site
Private Function SetTrustedSite(ByVal StrSiteName As String)
On Error GoTo Errhandle
Dim nKeyHandle, KeyValue, Iresult As Long
Dim StrkeyPath As String
StrkeyPath = "Software\Microsoft\Windows\CurrentVersion\Internet Settings\ZoneMap\Domains\"
StrkeyPath = StrkeyPath & SplitSiteName(StrSiteName)
KeyValue = 2
Call RegCreateKey(HKEY_CURRENT_USER, StrkeyPath, nKeyHandle)
Iresult = RegSetValueEx(nKeyHandle, "http", 0, REG_DWORD, KeyValue, 4)
If Iresult = 0 Then
MsgBox "You have accept http://" & StrSiteName & " as your Trusted Site!"
Else
MsgBox "Fail add http://" & StrSiteName & " as your Trusted Site!"
End If
Call RegCloseKey(nKeyHandle)
Exit Function
Errhandle:
MsgBox "Fail add http://" & StrSiteName & " as your Trusted Site!"
End Function

'// Split SiteName
'// "A.B.C.D.E" ----> "D.E/A.B.C"
'// "A.B.C.D" ----> "C.D/A.B"
'// "A.B.C" ----> "B.C/A"
'// "A.B" ----> "A.B"
'// "A" ----> "A"
Private Function SplitSiteName(ByVal StrSiteName As String) As String
Dim ArraySiteName
Dim IntArrayLen, I As Integer
Dim StrSplitSite As String

ArraySiteName = Split(StrSiteName, ".")
IntArrayLen = UBound(ArraySiteName)

If IntArrayLen > 1 Then
StrSplitSite = ArraySiteName(IntArrayLen - 1) & "." & ArraySiteName(IntArrayLen) & "\"
For I = 0 To IntArrayLen - 2
If I = 0 Then
StrSplitSite = StrSplitSite & ArraySiteName(I)
Else
StrSplitSite = StrSplitSite & "." & ArraySiteName(I)
End If
Next
SplitSiteName = StrSplitSite
Else
SplitSiteName = StrSiteName
End If

End Function

（出处：开发者俱乐部）